Pyridinium derivative, process for preparing it, use of it, pharmaceutical composition, process for preparing a parenteral formulation, and, methods of treating a diabetic patient and of preventing or treating diseases caused by diabetes and related complications with aging

摘要

"PYRIDINIUM DERIVATIVE, PROCESS FOR THE PREPARATION OF THE SAME, USE OF THE SAME, PHARMACEUTICAL COMPOSITION, PROCESS FOR THE PREPARATION OF A PARENTERAL FORMULATION, AND, METHODS OF TREATING A DIABETIC PATIENT AND PREVENTION OF TREATMENT OR TREATMENT OF DEATH OR TREATMENT OF DEATH OR TREATMENT. RELATED TO AGING ". The invention describes new compounds of the pyridinium series useful for the treatment of diabetes and vascular complications related to aging, including kidney disease, nervous disease, atherosclerosis, retinopathy, dermatological disorders and tooth discoloration, by rupture of preformed AGE, or their pharmaceutically acceptable salts. The invention also describes the process for the preparation of new compounds of the series and pharmaceutical composition comprising one or more of these compounds. The invention further describes a process for treating a diabetic patient by administering compounds either individually or in combination with drugs for diabetic therapy.