首页> 外国专利> pyridinium derivative, compound preparation process, compound use, pharmaceutical composition for treating diabetic complications and aging-related diseases, process for preparing a parenteral formulation, process for treating a diabetic patient by rupturing an age preformed within the patient, and process for preventing or treating diseases caused by diabetes and aging-related complications.

pyridinium derivative, compound preparation process, compound use, pharmaceutical composition for treating diabetic complications and aging-related diseases, process for preparing a parenteral formulation, process for treating a diabetic patient by rupturing an age preformed within the patient, and process for preventing or treating diseases caused by diabetes and aging-related complications.

机译:吡啶鎓衍生物,化合物的制备方法,化合物的用途,用于治疗糖尿病并发症和衰老相关疾病的药物组合物,制备肠胃外制剂的方法,通过破坏患者体内预先形成的年龄来治疗糖尿病患者的方法以及预防或治疗的方法糖尿病引起的疾病和与衰老相关的并发症。

摘要

"Pyridinium derivative, process for preparing it, use thereof, pharmaceutical composition, process for preparing a parenteral formulation, and methods of treating a diabetic patient and preventing or treating diseases caused by diabetes and complications. related to aging ". The invention discloses novel pyridinium series compounds useful for the treatment of diabetes and aging-related vascular complications, including kidney disease, nervous disease, atherosclerosis, retinopathy, dermatological disorders and discoloration of teeth by preformed age rupture, or pharmaceutically acceptable salts thereof. The invention also describes the process for the preparation of novel compounds of the series and pharmaceutical composition comprising one or more of these compounds. The invention further describes a process of treating a diabetic patient by administering compounds either individually or in combination with drugs for diabetic therapy.
机译:“吡啶鎓衍生物,其制备方法,其用途,药物组合物,肠胃外制剂的制备方法以及治疗糖尿病患者和预防或治疗由糖尿病和并发症引起的与衰老有关的疾病的方法”。本发明公开了新颖的吡啶鎓系列化合物,或其药学上可接受的盐,其可用于治疗糖尿病和与衰老相关的血管并发症,包括肾脏疾病,神经疾病,动脉粥样硬化,视网膜病,皮肤病和因预先形成的年龄破裂而使牙齿变色。本发明还描述了制备一系列新化合物的方法和包含一种或多种这些化合物的药物组合物。本发明进一步描述了通过单独地或与用于糖尿病治疗的药物组合施用化合物来治疗糖尿病患者的方法。

著录项

  • 公开/公告号BR9913746E8

    专利类型

  • 公开/公告日2018-05-02

    原文格式PDF

  • 申请/专利权人 TORRENT PHARMACEUTICALS LTD.;

    申请/专利号BR19999913746

  • 发明设计人 ALANGUDI SANKARANARAYANAN;

    申请日1999-10-15

  • 分类号C07D213/79;C07D213/80;A61K8;A61K8/49;A61K9/08;A61K9/20;A61K31/4425;A61K31/4427;A61K31/4436;A61K31/444;A61K31/455;A61K45/06;A61K47/02;A61K47/12;A61K47/26;A61K47/32;A61K47/34;A61K47/36;A61P1/02;A61P3/10;A61P9;A61P9/10;A61P13/12;A61P17;A61P27/02;A61P37;A61P43;A61Q11;A61Q19/08;C07D207;C07D213;C07D213/77;C07D213/81;C07D213/82;C07D213/87;C07D333;C07D401/06;C07D405/12;C07D409/06;C07D409/14;

  • 国家 BR

  • 入库时间 2022-08-21 12:53:30

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