首页> 外国专利> Compounds derived from 1 - aminoalquil - lactams, antagonists of Muscarinic receptors; Preparation procedure;Pharmaceutical composition comprising Said compound and use of the compound in the treatment of diseases associated with smooth muscle disorders.

Compounds derived from 1 - aminoalquil - lactams, antagonists of Muscarinic receptors; Preparation procedure;Pharmaceutical composition comprising Said compound and use of the compound in the treatment of diseases associated with smooth muscle disorders.

机译:衍生自1-氨基醇-内酰胺,毒蕈碱受体拮抗剂的化合物;制备方法;包含所述化合物的药物组合物,以及该化合物在治疗与平滑肌疾病有关的疾病中的用途。

摘要

This Invention relates to compounds that are antagonists of Muscarinic M2 / m3, which are represented by the formula where X, y, and Z are - O -, - S - or N - R5,And the other substituents are as defined in the specification, or individual isomers, prodrugs, non Racemic mixtures or Racemic isomers,And pharmaceutically acceptable salts or solvates of the same. The Invention also relates to pharmaceutical compositions containing such compounds.Processes for their Preparation and their use for the treatment of diseases associated with abnormalities in the muscuulo Smooth.
机译:本发明涉及作为Muscarinic M 2 / m 3拮抗剂的化合物,其由下式表示:其中X,y和Z为-O-,-S-或N-> R 5,且其他取代基如在定义中。规范或单个异构体,前药,非外消旋混合物或外消旋异构体,以及它们的可药用盐或溶剂化物。本发明还涉及含有这类化合物的药物组合物。其制备方法及其在治疗与平滑肌异常有关的疾病中的用途。

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