Stable Lyophilized Pharmaceutical composition comprising a muteina interleukin - 2 (IL - 2) and a Stabilizer mixture comprising histidine, Glycine and sucrose.

摘要

A stable Pharmaceutical composition comprising Human interleukin-2 or variant of the same and a Stabilizing amount of histidine.A Preferred formulation includes Glycine and sucrose and Variant II - 2 has a simple mutation, n88r in Lyophilized form, that is,With the Reconstruction with an aqueous diluent, produces a Solution having a pH ranging from about 5.0 to 6.5.