Subtilisin protease variants protease with amino acid replacement is determining table

摘要

The present invention relates to the variants of the subtilisin-like protease compared with their corresponding wild-type proteases with reduced immunogenicity. It is more particularly related to the variant of the amino acid sequence of the modification with wild-type amino acid sequence, wherein the amino acid sequence modified includes the substitution in one or more epitopes area. Washing and personal care composition the invention further relates to the mutated gene for encoding this variant and containing this variant.