首页> 外国专利> Isolated nucleic acid molecule encoding gp75, expression vector based thereon, polypeptide encoded thereby and vaccine containing such vector or polypeptide

Isolated nucleic acid molecule encoding gp75, expression vector based thereon, polypeptide encoded thereby and vaccine containing such vector or polypeptide

机译:编码gp75的分离的核酸分子,基于其的表达载体,由其编码的多肽以及含有该载体或多肽的疫苗

摘要

Disclosed is an isolated nucleic acid molecule encoding gp75, which molecule comprises a sequence cDNA encoding gp75 fragment as indicated in the description; polypeptide encoded by this molecule; an expression vector containing a DNA sequence that is substantial for vector replication and being connected with this molecule adapted for expression in a host; a vaccine for stimulating or increasing immune response in a subject to which it is administered and which contains this expression vector and/or a polypeptide, and in the end an effective amount of an adjuvant as well as a pharmaceutically acceptable carrier.
机译:公开了分离的编码gp75的核酸分子,该分子包含如说明书中所示的编码gp75片段的序列cDNA。该分子编码的多肽;一种表达载体,其含有对载体复制至关重要的DNA序列,并与适于在宿主中表达的该分子连接;用于刺激或增加受试者免疫应答的疫苗,该疫苗含有该表达载体和/或多肽,最后含有有效量的佐剂和药学上可接受的载体。

著录项

  • 公开/公告号CZ290278B6

    专利类型

  • 公开/公告日2002-07-17

    原文格式PDF

  • 申请/专利权人 SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH;

    申请/专利号CS19910000760

  • 发明设计人 HOUGHTON ALAN N.;

    申请日1991-03-21

  • 分类号C12N15/11;C12N15/63;A61K35/36;A61K31/65;

  • 国家 CZ

  • 入库时间 2022-08-22 00:45:42

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