ISOLATED NUCLEIC ACID ENCODING FEBP1, A VECTOR AND HOST CELL COMPRISING THE SAME, A METHOD OF PRODUCING A POLYPEPTIDE ENCODED BY THE SAME AND A METHOD OF CHARACERIZING BINDING MOLECULES isolated nucleic acid encoding FEBP1, a vector and host cell comprising the same, a method of producing a polypeptide encoded by the same, and a method of characterizing binding molecules

摘要

The invention concerns novel compounds and their pharmaceutical, diagnostic use or as pharmacological target. More particularly, it concerns the identification of partners of FE65 and the use thereof, or any compound capable of modulating, at least partly, their interaction with FE65 to regulate FE65 activity, and in particular the phenomenon of intracellular transport or of APP endocytosis.