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Combinations with immunosuppressive effects containing cyclooxygenase-2 inhibitors and 5-lipooxygenase inhibitors
Combinations with immunosuppressive effects containing cyclooxygenase-2 inhibitors and 5-lipooxygenase inhibitors
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机译:含有环氧合酶-2抑制剂和5-脂氧合酶抑制剂的免疫抑制作用组合
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摘要
This invention is in the field of a combination comprising a therapeutically-effective amount of a cyclooxygenase-2 inhibitor, a 5-lipoxygenase inhibitor and an immunosuppressive drug selected from antiproliferative agents, antiinflammatory-acting compounds and inhibitors of leukocyte activation. This combination may be used, for example, to suppress the immune response associated with organ transplantation, graft versus host disease, and conditions with underlying autoimmune or inflammatory reactivities or responses.
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