SUBSTITUTED IN POSITION 6 INDOLINONES, THEIR RECEIVING AND THEIR APPLICATION AS MEDICINE PRODUCTS

摘要

The application describes substituted indolinones of general formula (I) in position 6 wherein R-R and X have the meanings indicated in claim 1, their isomers and their salts, first of all their physiologically acceptable salts, which have valuable pharmacological properties, first inhibitory effect on various receptor tyrosine kinases and cyclin / CDK complexes, as well as on the proliferation of endothelial cells and various tumor cells, and also describes the drugs containing these compounds, the use of these compounds and their The international application was published along with an international search report.