Compounds, compositions and Methods For Stimulating Growth and elongation of Neurons.

摘要

The Invention relates to compounds of the formula I where related to alquileno where (= CH2 groups can be replaced by SO2, so, S, and B = AR, rent, alquenilo,Cicloalquenilo substituted cycloalkyl or straight or branched or not; the object of the invention is to provide neurotrophic compounds are small molecules that have an affinity toward inmunofilinasFKBP type, once attached to these Proteins, neurotrophic compounds are potent inhibitors of the Enzymatic activity particularly associated with the activity of the rotamasa,It is also an objective of the present Invention provide compounds that have no antidepressant activity in addition to its neurotrophic activity.Also provided are methods for treating patients with neurological trauma as a result of injury or as a result of conditions such as: headache, muscular dystrophy)Bell's palsy, Parkinson's, Alzheimer's, sclerosis, stroke and other Neurological diseases such as: damage to neurons, the nerve injury of the spine, Hair Loss, etc.