6-(aryl og heteroaryl)oksymetylnaftalen-2-karboksimidamid derivater, fremstilling og terapeutisk anvendelse derav

摘要

The present invention relates to compounds of general formula (i) (see appended drawing in bopi) in which r1 represents a hydrogen atom or an amino group or a group (c1 - c4) alkyl, or a group (c1 - c6) alkoxycarbonyl group, r2 represents a group (c1 - c6) alkyl, phenyl or benzyl, or a group - ch2 q, where q is a heterocyclic group, r3, r5 represent, independently of one another, either a hydrogen atom or a group (c1 - c4) alkyl, or a group - cooh, r4 represents a hydrogen atom or a group (c1 - c4) alkyl, or a group - (ch2), p - coor8, z represents a group - ch -, or a nitrogen atom. Processes of preparation and application in therapeutics.