首页>
外国专利>
Modified hepatitis B core protein conjugate, particles thereof, inoculum and process for inducing antibodies
Modified hepatitis B core protein conjugate, particles thereof, inoculum and process for inducing antibodies
展开▼
机译:修饰的乙肝核心蛋白缀合物,其颗粒,接种物和诱导抗体的方法
展开▼
页面导航
摘要
著录项
相似文献
摘要
In the present invention, there is disclosed a strategically modified hepatitis B core protein, where an insert is provided, preferably in an immunodominant region of the nucleocapsid protein, containing a chemically reactive amino acid residue. The modified hepatitis B core protein or its aggregated nucleocapsid protein particles can be pendently linked to a hapten to form a modified nucleocapsid conjugate. Such a conjugate is useful in the preparation of vaccines or antibodies. The modified hepatitis B core protein can also be modified to include a T cell epitope.
展开▼