ABSORBABLE STRUCTURES FOR LIGAMENT AND TENDON REPAIR.

摘要

A FULLY ABSORBABLE PROSTHESIS (1) FOR THE REPAIR OF DAMAGED LIGAMENTS AND/OR TENDONS IN THE FORM OF A MULTILAYER SPIRAL ROLL COMPRISING THE FOLLOWING SPIRAL LAYERS: A FORAMINOUS LAYER (2) OF A SYNTHETIC BIOABSORBABLE MATERIAL; A BIOABSORBABLE FILM (3); AND A LAYER (4)''OF A BIOABSORBABLE BIOPOLYMER SPONGE. THE INVENTION ALSO PROVIDES A METHOD OF MAKING SUCH A PROSTHESIS, COMPRISING THE STEPS OF: PROVIDING A LAMINATE OF A FORAMINOUS LAYER OF BIOABSORBABLE MATERIAL AND A BIOABSORBABLE FILM; COATING THE LAMINATE WITH A LAYER OF AN AQUEOUS GEL COMPRISING A. BIOABSORBABLE POLYMER; ROLLING UP THE LAMINATE AND THE GEL LAYER INTO A SPIRAL ROLL, FOLLOWED BY DRYING THE GEL TO FORM A LAYER OF BIOABSORBABLE SPONGE. THE FORAMINOUS LAYER (2) PREFERABLYCOMPRISES A SYNTHETIC BIOABSORBABLE POLYMER HAVING HIGH TENSILE STRENGTH. THE BIOABSORBABLE FILM (3) AND SPONGE LAYER (4) PREFERABLY COMPRISE A CHEMOTACTIC BIOPOLYMER SUCH AS COLLAGEN.(FIG. 1)