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Transgenic mice containing huntingtin interacting protein gene disruptions
Transgenic mice containing huntingtin interacting protein gene disruptions
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机译:含有亨廷顿蛋白相互作用蛋白基因破坏的转基因小鼠
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摘要
The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a HIP1 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
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