首页> 外国专利> A novel polypeptide-human branched chain alpha-keto acid dehydrogenase e1-beta subunit 9 and the polynucleotide encoding said polypeptide

A novel polypeptide-human branched chain alpha-keto acid dehydrogenase e1-beta subunit 9 and the polynucleotide encoding said polypeptide

机译:新型多肽-人支链α-酮酸脱氢酶e1-β亚基9和编码所述多肽的多核苷酸

摘要

The invention discloses a new polypeptide-human branched chain alpha-keto acid dehydrogenase E1-beta subunit 9, the polynucleotide encoding said polypeptide, and a process for producing the polypeptide by recombinant DNA technology. It also discloses methods of applying the polypeptide for the treatment of various diseases, such as diabetes, organic acidemia, tumor, development disorder, inflammation, immune disorders and hemopathy. This invention also discloses antagonist against said polypeptide and thereof therapy uses. In addition, it refers to the use of said polynucleotide encoding this new human branched chain alpha-keto acid dehydrogenase E1-beta subunit 9.
机译:本发明公开了一种新的多肽-人支链α-酮酸脱氢酶E1-β亚基9,该多肽的多核苷酸,以及通过重组DNA技术生产该多肽的方法。它还公开了将多肽用于治疗各种疾病的方法,所述疾病例如糖尿病,有机酸血症,肿瘤,发育障碍,炎症,免疫障碍和血液病。本发明还公开了针对所述多肽的拮抗剂及其治疗用途。另外,它涉及编码所述新的人支链α-酮酸脱氢酶E1-β亚基9的所述多核苷酸的用途。

著录项

  • 公开/公告号AU6728401A

    专利类型

  • 公开/公告日2001-11-12

    原文格式PDF

  • 申请/专利权人 SHANGHAI BIOWINDOW GENE DEVELOPMENT INC.;

    申请/专利号AU20010067284

  • 发明设计人 YI XIE;YUMIN MAO;

    申请日2001-04-28

  • 分类号C12N15/53;C07K14/47;

  • 国家 AU

  • 入库时间 2022-08-22 00:39:35

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