Method of typing a biological sample comprising contacting the sample with one or more antibodies specific for any of the following polymorphisms: (i) R220 of PGM1, (ii) C220 of PGM1, (iii) Y419 of PGM1, (iv) H419 of PGM1, (v) D416 T420 of GC, (vi) E416 T420 of GC, (vii) D416 K420 of GC, (viii) H101 of AAT, (ix) R101 of AAT, (x) V264 of AAT, (xi) E264 of AAT, (xii) K342 of AAT, (xiii) E342 of AAT, (xiv) V213 of AAT and (xv) A213 of AAT, and determining whether the antibody binds a protein in the sample, binding of the antibody to the protein indicating that the sample contains a protein possessing the polymorphism for which the antibody is specific.
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