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METHODS AND COMPOSITIONS FOR IDENTIFYING MORPHOGENIC PROTEIN ANALOGS USING MORPHOGENIC PROTEIN RESPONSIVE INHIBITORY ELEMENTS
METHODS AND COMPOSITIONS FOR IDENTIFYING MORPHOGENIC PROTEIN ANALOGS USING MORPHOGENIC PROTEIN RESPONSIVE INHIBITORY ELEMENTS
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机译:利用形态发生蛋白反应性抑制元素鉴定形态发生蛋白类似物的方法和成分
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摘要
The present invention relates generally to methods and compositions for identifying morphogenic protein analogs. In one embodiment, this invention relates to an osteogenic protein reponsive transcription inhibitory element. This invention also relates to the identified morphogenic protein analogs which can mimic the biological effects of morphogenic proteins, particularly those relating to the BMP family such as osteogenic protein (OP-1), on the regulation of gene expression and tissue inductive capabilities.
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