ANTISENSE RNA EXPRESSION STRATEGIES EFFECTIVE AGAINST STREPTOCOCCUS THERMOPHILUS BACTERIOPHAGE
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机译:抗链球菌嗜热菌噬菌体的反义RNA表达策略
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摘要
Recombinant bacteria containing nucleotide sequences encoding Streptococcus thermophilus phage helicase and primase genes expressed in the antisense orientation and methods of making and using the same are disclosed. Replication of bacteriophage infecting this bacterial cell, can be inhibited or decreased by constitutively expressing, the antisense oligonucleotide encoding for S. thermophilus phage helicase or primase.
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