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Tumor suppressor polypeptide issued from CHC1-L (chromosome condensation 1-like)

机译:CHC1-L发出的抑癌多肽(染色体缩合1样)

摘要

The present invention relates to a new polypeptide useful for the treatment of metastatic disease, and more particularly of prostate cancer.;This polypeptide is of about 15 to about 30 amino acids, and corresponds to the protein fragment which is encoded by the 5' end of the tumor suppressor gene CHC1-L.;The present invention also relates to a nucleotide sequence encoding for said polypeptide and vector, host cell and pharmaceutical composition including said polypeptide or nucleotide sequence.;It is also an object of the present invention to develop a new method, and the corresponding kit, for the prostate in vitro diagnosis.
机译:本发明涉及一种用于治疗转移性疾病,尤其是前列腺癌的新多肽。该多肽具有约15至约30个氨基酸,并对应于由5'端编码的蛋白质片段。本发明还涉及编码所述多肽和载体的核苷酸序列,宿主细胞和包含所述多肽或核苷酸序列的药物组合物。本发明的目的还在于开发一种用于前列腺体外诊断的新方法和相应的试剂盒。

著录项

  • 公开/公告号EP1201680A2

    专利类型

  • 公开/公告日2002-05-02

    原文格式PDF

  • 申请/专利权人 UROGENE SOCIÉTÉ ANONYME;

    申请/专利号EP20010400715

  • 申请日2001-03-20

  • 分类号C07K9/00;C07K14/47;C12N15/11;C12N15/62;C12N15/63;A61K38/00;A61K48/00;A61P35/00;

  • 国家 EP

  • 入库时间 2022-08-22 00:33:28

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