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EVOLUTION AND USE OF ENZYMES FOR COMBINATION AND MEDICINAL CHEMISTRY
EVOLUTION AND USE OF ENZYMES FOR COMBINATION AND MEDICINAL CHEMISTRY
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机译:酶的结合化学和化学演化与应用
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摘要
The present invention provides recombinate derivative enzyme to can be used for the oforganic molecules of biocatalysis synthesis of derivatives, including medicinal lead compound. The organic molecule of the derivative enzyme such as functional group of modifications or substitutions catalysis reaction is recombinated without considering, or addition chemical part to previously existing functional group. Using recombinant enzyme library, so that people is obtained enzyme, be catalyzed the formation of organic molecules derivitization, therefore it cannot be made to use unique native enzyme in another manner.
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