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Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway
Generation and/or reduction of new lung tissue in an affected lung, by modulation of the Wnt-pathway
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机译:通过调节Wnt途径在受影响的肺中生成和/或减少新的肺组织
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摘要
The present invention provides a means to influence the formation and/or reduction of new lung cells, by influencing a Wnt-pathway in an alveolar type II cell and/or alveolar type II tumor cell from said lung. Therefore, the invention provides a composition comprising a nucleic acid capable of binding at least a functional part of a nucleic acid encoding a protein which is involved in a Wnt-pathway in said cell, said binding influencing said Wnt-pathway.;A composition of the invention may also comprise a protein capable of binding at least a functional part of a protein which is involved in a Wnt-pathway in said cell, or at least a functional part of a nucleic acid encoding a protein which is involved in a Wnt-pathway in said cell, said binding influencing said Wnt-pathway.;A composition of the invention is suitable for the preparation of a medicament against emphysema, Respiratory Distress Syndrome and/or lung cancer.
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