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CLONING, EXPRESSION AND CHARACTERISATION OF A GENE EXPRESSED IN TUMOUR CELLS AND INVOLVED IN THE REGULATION OF THE IMMUNE RESPONSE
CLONING, EXPRESSION AND CHARACTERISATION OF A GENE EXPRESSED IN TUMOUR CELLS AND INVOLVED IN THE REGULATION OF THE IMMUNE RESPONSE
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机译:在肿瘤细胞中表达并参与免疫应答调节的基因的克隆,表达和表征
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摘要
The invention concerns the identification and the characterisation of a novel gene expressed in tumour cells and involved in the regulation of the immune response, the cloning and the characterisation of its cDNA and the corresponding polypeptides. The invention also concerns vectors containing a nucleic acid coding for said gene, cells transformed by said vectors and diagnostic methods and selection methods of a chemical or biological compound capable of directly or indirectly interacting with a nucleic acid or a polypeptide of the invention. The invention further concerns compounds for treating immune pathologies, in particular autoimmune diseases and cancer.
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