45- 45-DIARYLOXAZOLE COMPOUNDS WITH PROSTAGLANDIN I2PGI2 AGONISTIC ACTIVITY

摘要

The present invention relates to heterocyclic compounds and pharmaceutically acceptable salts thereof of formula (I), also it relates to the use thereof as a medicine.; Formula I; Wherein R ¹ is carboxy or protected carboxy,; R ² and R ³ is an aryl group which may have a substituent,; X is hydrogen, and R ⁵ (wherein R ⁵ is hydroxy or protected hydroxy) the oxygen or one pair,; A ¹ and A ² are each lower alkylene.