Orally Administrable Pharmaceutical Preparation Having Therapeutic Effect on Gastrointestinal Disorders Comprising Coated Ranitidine Bismuth Subcitrate and Sucralfate

摘要

PURPOSE: Provided is an orally administrable pharmaceutical preparation having therapeutic effect on gastrointestinal disorders which comprises as active ingredients ranitidine, bismuth subcitrate and sucralfate, wherein the ranitidine is coated with a coating agent to have a film dissolution time ranging from 20 to 90 minutes. CONSTITUTION: The orally administrable pharmaceutical preparation has therapeutic effect on gastrointestinal disorders which comprises as active ingredients ranitidine, bismuth subcitrate and sucralfate, wherein the ranitidine is coated with a coating agent to have a film dissolution time ranging from 20 to 90 minutes, preferably 30 to 70 minutes; the coating agent is an enteric coating agent selected from the group consisting of hydroxypropyl methylcellulose, methylcellulose and Eudragit; and the preparation is pharmaceutically manufactured into granules, capsules, tablets or double-layer tablets comprising coated tablet cores.