Method of manufacturing a transplanted body having a sheet-like arrangement and a transplantation device for forming a rotational transplanted body

摘要

The method of implanting the graft in the subretinal region of the host eye involves preparing the graft by obtaining a cell population from the feeder tissue in such a way as to maintain a cell population with the same tissue and cell polarity as is present in normal tissue. The cell population is in sheet form and assembled with a relatively thin flexible and flexible carrier composed of a nontoxic flexible composition that substantially dissolves at body temperature to form the graft. The graft has sufficient flexibility and flexibility to coil to form helix 76 without disturbing the tissue and polarity of the cell. The method further includes coiling the graft and subsequently forming helix 76 with free convolutions about each other such that the helix 76 can be unwound so that the graft can be substantially in its original sheet form. do. An incision is made in the host eye to insert helix 76. The incision in the eye is smaller than necessary to insert an uncoiled sheet-like graft. One end of the helix is first inserted through the incision into the host eye and moved to a position between the retina and the underlying tissue. After insertion, the coil of helix 76 is released and placed in the form of a sheet between the retina of the host eye and the underlying tissue. Then the incision is closed.