where R is CH3:R1-CH3,OC2H5; R is C6H5:R1-OC2H5,C6H5,CF2H; R is CF3:R1-C6H5,n-C6H4Cl; that are products used for synthesis of biologically active substances. Compounds are synthesized by interaction of 1,3-dehydroadamantane with corresponding β-diketone or ketoester in the mole ratio of reagents = 1 : (1.5-2) in diethyl ether medium as an inert solvent, at its boiling point for 1-3 h. The yield of end compounds is 81-98%. EFFECT: simplified method, high yield. 11 ex"/>
METHOD OF SYNTHESIS OF ADAMANTYL-CONTAINING amp;beta;-DIKETONES AND KETOESTERS
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METHOD OF SYNTHESIS OF ADAMANTYL-CONTAINING amp;beta;-DIKETONES AND KETOESTERS
METHOD OF SYNTHESIS OF ADAMANTYL-CONTAINING amp;beta;-DIKETONES AND KETOESTERS
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机译：含有金刚烷基的β-二酮和酮基酯的合成方法
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摘要
FIELD: organic chemistry, chemical technology. SUBSTANCE: invention relates to derivatives of adamantine, namely to a novel method of synthesis of β-dicarbonyl derivatives of adamantine of the general formula: where R is CH3:R1-CH3,OC2H5; R is C6H5:R1-OC2H5,C6H5,CF2H; R is CF3:R1-C6H5,n-C6H4Cl; that are products used for synthesis of biologically active substances. Compounds are synthesized by interaction of 1,3-dehydroadamantane with corresponding β-diketone or ketoester in the mole ratio of reagents = 1 : (1.5-2) in diethyl ether medium as an inert solvent, at its boiling point for 1-3 h. The yield of end compounds is 81-98%. EFFECT: simplified method, high yield. 11 ex
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机译：领域：有机化学，化学技术。物质：本发明涉及金刚烷衍生物，即涉及一种新的合成金刚烷的β-二羰基衍生物的方法：，其中R为CH 3 ：R 1 -CH 3 ，OC < Sub> 2 H 5 ; R是C 6 H 5 ：R 1 -OC 2 H 5 ， C 6 H 5 ，CF 2 H; R是CF 3 ：R 1 -C 6 H 5 ，nC 6 H 4 Cl; 是用于合成生物活性物质的产品。通过在惰性溶剂二乙醚介质中，在沸点为1-3的条件下，通过试剂摩尔比为1：1：（1.5-2）的1,3-脱氢金刚烷与相应的β-二酮或酮酸酯的相互作用来合成化合物H。最终化合物的产率为81-98％。效果：简化方法，高产。 11前
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