LIGAND BINDING RECEPTOR STEM OF POLYMERIC IMMUNOGLOBULIN (PIGR) OF CELL SPECIFICALLY, METHOD OF INCORPORATION OF LIGAND IN CELL AND METHOD OF ATTACHMENT OF LIGAND TO CELL EXPRESSING RECEPTOR OF POLYMERIC IMMUNOGLOBULIN

摘要

FIELD: biotechnology, pharmacy. SUBSTANCE: invention relates to ligand and methods of its specific binding with receptor stem of polymeric immunoglobulin (pIgR) of cell under condition that ligand does not bind secretory component pIgR under physiological conditions practically. Ligand can be directed on cell, into cell or for passing through its and can comprise biologically active substances. Invention can be used for delivery of therapeutic and diagnostic compositions on epithelial mucosa cells, into these cells or through their. EFFECT: improved method of incorporation, valuable properties of ligand. 28 cl