Obstruction of the development of ovaries, puberty or sexual infantism

摘要

A method of inhibiting ovarian dysgenesis, delayed puberty, or sexual infantilism comprising administering to a human in need thereof an effective amount of a compound having the formula CHEM wherein R1 and R3 are independently hydrogen, -CH3, CHEM wherein Ar is optionally substituted phenyl; R2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino; or a pharmaceutically acceptable salt of solvate thereof.