Carrier having immobilized antigens/antibodies useful for diagnosing infections, comprises a surface formed of calcium phosphate based compound, and antigens/antibodies immobilized to the surface

摘要

A carrier (I) with immobilized antigens (Ags) or antibodies (Abs), with a surface (S) formed of a calcium phosphate based compound, and Ags/Abs each having a portion that is irrelevant to the Ag-Ab reaction, where each of Ags and Abs are immobilized to (S) through its irrelevant portion, and (S) has a portion where the Ags and Abs are not immobilized, is new. A carrier (I) having immobilized Ags or Abs, comprises a surface (S) which is formed of a calcium phosphate based compound, and Ags or Abs each having a portion that is irrelevant to the Ag-Ab reaction, where each of the Ags and Abs are immobilized to (S) through its irrelevant portion, and (S) has a portion where the Ags and Abs are not immobilized, and at least a part of the portion of (S) is coated with a protein having low interactions with Ags or Abs. An Independent claim is also included for manufacture (M) of (I) by immobilizing Ags or Abs to a surface of a carrier which is formed of a calcium phosphate base compound through portions of Ags or Abs that are irrelevant to the Ag-Ab reaction, and coating a portion of the surface of the carrier, where Ags or Abs are not immobilized with a protein having low interaction with Ags or Abs.