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Cohesive immunoassay methods and reagents with good reproducibility

机译:具有良好重现性的内聚免疫测定方法和试剂

摘要

The agglomeration immunoassay method which makes the agglomeration and inhomogenization of an insoluble carrier particle such as latex stabilize and uniformize, and has excellent reproducibility, and an immunoassay reagent used therefor. An insoluble carrier in a test sample is bound to an insoluble carrier particle in the absence of an antigen or antibody, and an antibody or antibody complex that specifically reacts with the antigenic substance is combined to selectively coagulate the insoluble carrier particles In the aggregated immunoassay method, a monomer having a phosphorylcholine group and a vinyl group such as 2-methacryloyloxyethyl phosphorylcholine alone was polymerized, or a monomer having a phosphorylcholine group and a vinyl group, and methacrylic acid A polymer copolymerized with a monomer having a vinyl group such as n-butyl is used.
机译:使不溶性载体粒子如胶乳的团聚和不均一化稳定且均一且重现性优异的团聚免疫分析方法及其所用的免疫分析试剂。在不存在抗原或抗体的情况下,将测试样品中的不溶性载体结合到不溶性载体颗粒上,并与抗原性物质特异性反应的抗体或抗体复合物结合在一起,以聚集免疫测定法选择性地凝结不溶性载体颗粒。然后,将具有磷酰胆碱基团和乙烯基的单体,例如2-甲基丙烯酰氧基乙基磷酰胆碱单独聚合,或者将具有磷酰胆碱基团和乙烯基的单体与甲基丙烯酸A与具有乙烯基的单体共聚的聚合物,例如n-使用丁基。

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