Gene encoding tumor suppressor gene p51 promoter region and use thereof

摘要

According to the present invention, a gene encoding a promoter region of a protein p51 exhibiting cell death inducing ability and a gene encoding a 5 dash untranslated region of p51 are provided. These genes are useful for diagnosis and treatment of diseases including cancers arising from abnormal cell proliferation control. In addition, antisense DNA and antisense RNA of these genes, nucleic acid probes comprising some or all of these genes, and methods for detecting the gene of the invention or similar genes using the nucleic acid probe The transgenic body introduced the bright gene, and the screening method of the drug using these are provided. These genes are useful for diagnosis and treatment of diseases such as cancer.