TRANSGENIC RAT FOR DETECTING MUTATION, METHOD FOR PRODUCING THE SAME AND METHOD FOR ASSAYING MUTATION

摘要

PROBLEM TO BE SOLVED: To provide a transgenic rat usable for mutation assay, to provide a method for efficiently producing the transgenic rat and to provide a method for detecting mutagenicity of a compound by using the transgenic rat. ;SOLUTION: The transgenic rat for detecting mutation is characterized by introducing a gene including a replicator and a reporter gene of a lambda phage, wherein the replicator can be replicated in a prokaryotic cell.;COPYRIGHT: (C)2003,JPO