首页> 外国专利> Antigenic peptides, such as for G protein-coupled receptors (GPCRS), antibodies thereto, and systems for identifying such antigenic peptides

Antigenic peptides, such as for G protein-coupled receptors (GPCRS), antibodies thereto, and systems for identifying such antigenic peptides

机译:诸如G蛋白偶联受体(GPCRS)的抗原肽,其抗体以及用于鉴定此类抗原肽的系统

摘要

The present invention provides antigenic peptides for GPCRs and antibodies relating thereto, and related systems, methods, compositions, and the like, such as diagnostics and medicaments. Where antibodies against a given GPCR are not known, the present invention provides such antibodies, and preferred antigenic sequences for producing such antibodies. Where antibodies against a given GPCR are known, the present invention provides preferred antigenic peptides for producing antibodies that exhibit improved specificity, affinity or capacity to perform antibody-related actions relative to the known antibodies.
机译:本发明提供了用于GPCR的抗原肽和与其相关的抗体,以及相关的系统,方法,组合物等,例如诊断剂和药物。在针对给定GPCR的抗体未知的情况下,本发明提供了此类抗体,以及用于产生此类抗体的优选抗原序列。当已知针对给定GPCR的抗体时,本发明提供了优选的抗原肽,用于产生相对于已知抗体表现出提高的特异性,亲和力或执行抗体相关作用的能力的抗体。

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