Monoclonal antibody which inhibits transendothelial migration of human mononuclear leukocytes

摘要

The present invention relates to a monoclonal antibody against human mononuclear leukocytes which is capable of inhibiting transmigration of human mononuclear leukocytes after their adhesion to vascular endothelial cells, and to a hybridoma producing this antibody, and which can be used for studies to elucidate the mechanism of inflammatory reaction, and the diagnosis and therapy of inflammatory diseases.