Efficient Synthetic routes for the preparation of protease inhibitors of rhinovirus.

摘要

Efficient Synthetic routes for the preparation of rhinovirus protease inhibitors of Formula 1, as well as the intermediate clavesutiles in those Synthetic routes.The compounds of Formula 1, as well as lascomposicione s Pharmaceuticals containing these compoundsAre years or the treatment of patients infected with one or more other picornaviruses. The substituents R1 to R6 Z, Z1, are defined in the specification.