A vehicle biocompatible Stable non-aqueous single Phase, non aqueous formulations comprising at least one vehicle and suspended in the same beneficial Agent and Methods for preparing the vehicle and formulations. .

摘要

A biocompatible viscous Vehicle Stable non-aqueous single Phase, suitable for the suspension of beneficial agents and to dispense the beneficial Agent homogeneously over a long period of time the body temperature and low flow rates.The viscous Vehicle includes at least two components selected from the group consisting of a Solvent, a Surfactant and a Polymer. Formulations comprising at least a beneficial Agent, e.g., a Peptide, a Protein, nucleotide, a hormone, a virus or Antibody, etc.Uniformly Suspended in the vehicle, and are suitable for being stored at temperatures ranging between cold and body temperature for prolonged periods of time.And to be managed uniformly from the provisions for the Administration of drugs with a Velocity Shear at the exit between 1 and 1 x 10 - 7 S - 1; and Methods for preparing the vehicle and formulations.