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Replaced imidazole y neuropeptide y5 receptor y5 antagonists
Replaced imidazole y neuropeptide y5 receptor y5 antagonists
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机译:替代咪唑γ神经肽y5受体y5拮抗剂
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摘要
"IMMEDAZOLE Y NEUROPEPTIDE Y RECEPTOR Y5 ANTAGONISTS". Compounds of formula (I) or a pharmaceutically acceptable salt, solvate or N-oxide thereof, wherein X is = CH- or = N-; Y is H, halogen, trialoalkyl, alkyl, alkenyl, cycloalkyl, cycloalkyl, SH, -S-alkyl or -CN. R is alkyl, -CF-3-, cycloalkyl, heterocycloalkyl, heterocycloalkylalkyl, heteroarylalkyl or adamantyl or optionally substituted phenyl, phenoxyalkyl, phenylthioalkyl, pyridyl, thienyl, thiazolyl, pyrazinyl, 1,2,5,6-tetrahydropyridine or formula (A). wherein R 10 and R 11 are hydrogen, alkyl or together form a cycloalkyl, are disclosed, as well as pharmaceutical compositions and methods of using said compounds in the treatment of eating disorders and diabetes.
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