SUBSTITUTED IMIDAZOLE NEUROPEPTIDE Y Y5 RECEPTOR ANTAGONISTS

摘要

COPOUND OF THE FORMULA IOR A PHARMACEUTICALLY ACCETABLE SALT, SOLVATE OR N-OXIDE THREOF, WHREIN X IS =CH- OR =N-Y IS H, HALOGEN, TRIHALOALKYL, ALKYL, ALKENYL, CYCLOALKYL, CYCLOAKUL, SH, -S-ALKYL, OR -CN.R IS ALKYL, -CF3, CYCLOALKYL, HETEROCYCLOALKYL, HETEROCYCLOALKYL-ALKYL, HETEROARYALKYL OR ADANMANTYL OR OPTIONALLY SUBSITUTES PHENYL, PHENOXYALKYL, PHENYLTHIOALKYL, PYRIDYL, THIENYL, THIAZOLYL, PYRAZIYL, 1,2,5,6-TETRAHYDROPYRIDINE OR , WHEREIN R10 AND R11 ARE HYDROGEN, ALKYL OR TOGETHER FORM A CYCLOALKYL, ARE DISCLOSED, AS WELL AS PHARMACEUTICAL COMPOSITIONS AND METHODS OF USING SAOD COMPOUNDS IN THE TREATMENT OF EATING DISORDERS AND DIABETES.