A compound derived from Mandelic acid, its Pharmaceutical Composition and preparation procedure, useful for the inhibition of thrombin.To treat Thrombosis and Blood Hypercoagulable and / or tissues.

摘要

A compound of formula I and their Derivatives (including pharmaceutically acceptable prodrugs), which are useful as such or as prodrugs,As competitive inhibitors of Trypsin like proteases, such as thrombin, and in particular, in the treatment of conditions where inhibition of Thrombin is required (e.g.Example Thrombosis) or as anticoagulants.