A process for the preparation of a starch hydrolyzate having a low polymolecularity index, a novel starch hydrolyzate and its use in the preparation of an osmotic agent for peritoneal dialysis

摘要

Prodn. of starch hydrolysates with a low `polymolecularity index' (PI = Mw/Mn) comprises: (a) subjecting a waxy starch milk to acid hydrolysis to give a hydrolysate with a dextrose equivalent (DE) of 8-15; (b) opt. further hydrolysing the acid hydrolysate with bacterial alpha -amylase to give a hydrolysate with a DE of 11-18; (c) chromatographing the hydrolysate on macroporous cation-exchange resins in alkali(ne earth) metal form; and (d) collecting the hydrolysate excluded during the chromatography step. Also claimed is a waxy starch hydrolysate, opt. hydrogenated or hydrolysed, which is completely soluble in water and has a PI 2.8 (esp. 2.5), a Mw of 8000-22,500 (esp. 12,000-20,000) and a Mn 8000, where Mn = 1/Ä (the fractional wt. of each mol.)/(the mol. wt. of each mol.)