Dry powder inhalers (Picture 1) with integrated active energy patient assist dispersal systems are configured with control systems which provide adjustable energy output responsive to the user's inspiratory capabilities and/or the flowability of the dry powder being administered. The multi-dose dry drug package (Picture 2) a piezoelectric polymer substrate which flexes to deform and provide mechanical oscillation in a selected region of the package corresponding to the dry powder drug which is dispersed during inhalation by a user. Control system (Picture 12) employs fuzzy logic to relate in response to a user's inspiratory effort.
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