Cyanuric compounds in disease groups associated with unwanted citoquines activity

摘要

It refers to a triazole compound in the formula; in this compound, R1 is tar, beryllium, asphalt, ISO tar, ISO propene, ISO acrylonitrile, ISO propene, ISO propene, ISO propene, ISO propene, propylene, CN, or3, SR3, SO3, so2r3, nr3r4; m is 0-5; q is a; R2 is a; R2 is h, tar, alquenilo, asphalt, ISO tar, ISO propene, ISO propene, ISO acrylonitrile, ISO acrylonitrile, ISO propyl, ISO acrylonitrile, ISO propyl, ISO acrylonitrile, ISO propyl, ISO propyl Or3, SR3, SO3, among others; X, y, CR2, N; Z, CR2, N3, O, s; a is h, tar, aluminum, tar, tar, cyclopentadiene, cyclopentadiene, etc.; a is a link; B is h, tar, aluminum, tar, tar, tar, etc.; B is a link; R3 is h, tar, alquenilo, tar, tar, tar, tar, tar, tar, tar, tar, tar, tarBlue Nile, bicycle, etc. - [1,4 - [1 - [1,4 - [1,4 - [1 - [3]]]]]]] - 3 - [1, ofenil) - 5 - [2 - (ISO propilamino) pirimidin-4-il] etoximetyl - [1, 2, 3] triazol, There are others These compounds inhibit the release of cellular inflammation, such as Interlequina-1 and tumor necrosis factor, and can be used to treat osteoarthritis, rheumatoid arthritis, and congestive heart failure.