首页> 外国专利> 3 - (3R, 4R) - 4-methyl-3 - methyl - (7h pirrolo 2, 3-d pirimidin-4-il) - amine - piperidin-1-il} - 3-oxo-propionitrilo

3 - (3R, 4R) - 4-methyl-3 - methyl - (7h pirrolo 2, 3-d pirimidin-4-il) - amine - piperidin-1-il} - 3-oxo-propionitrilo

机译:3-(3R,4R)-4-甲基-3- [甲基-(7h吡咯并[2,3-d]嘧啶-4-基)胺]哌啶-1-基} -3-氧丙腈

摘要

It refers to the crystal salt form of 3 - (3R, 4R) - 4-methyl-3 - [methyl - (7h pirrolo [2, 3-d] pirimidin-4-il) - amine] - piperidin-1-il} - 3-oxo-propionyl, including X-ray derivatives of fine crystals expressed in degrees 2-o-5, 7, 16, 1, 20, 2 and 20.5. Its characteristic is that its initial temperature is between 199 ℃ and 206 ℃. It also refers to a kind of inhibiting the pharmacological synthesis of quinase protein, which helps to treat organ transplantation, sclerosis, arthritis, type 1 diabetes and other rejection related diseases.
机译:它是指3-(3R,4R)-4-甲基-3-[甲基-(7h吡咯并[2,3-d] pirimidin-4-il)-胺]-哌啶-1-il的晶体盐形式}-3-氧代丙酰基,包括以2-o-5、7、16、1、20、2和20.5表示的精细晶体的X射线衍生物。它的特点是其初始温度在199℃至206℃之间。它也指抑制奎纳酶蛋白的药理合成,有助于治疗器官移植,硬化症,关节炎,1型糖尿病和其他与排斥反应有关的疾病。

著录项

  • 公开/公告号PE20030807A1

    专利类型

  • 公开/公告日2003-09-22

    原文格式PDF

  • 申请/专利权人 PFIZER INC.;

    申请/专利号PE2002001162

  • 发明设计人 LI ZHENG JANE;FLANAGAN MARK EDWARD;

    申请日2002-12-03

  • 分类号C07D487/04;A61K31/519;

  • 国家 PE

  • 入库时间 2022-08-22 00:01:34

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