Pharmacological combinations include an agonist for adenosine AA receptor and an agonist for phenyladrenaline receptor

摘要

1. It refers to (a) an equation 1 hypnotic agent for adenosine AA receptor, wherein R1 is h, C1-C6 tar and phenyl, northwest Africa; R2 is h, C1-C6 tar; a is C1-C6 tar; R3 is h, C1-C6, coor4, CN, conr4r4r4, cyclo-c8, phenyl, etc.; r4quies h, C1-C6, cyclohexane, C8; R5 is C1-C6, C1-C6, cycloquilo C1-C6, phenyl; R6 is h, C1-C6, cycloquilo c3-c8, phenyl, etc.; R7 is C1-C6, cycloquilo c3-c8, phenyl, naftio, het; m is 0-2. A formula compound 9 - [(2R, 3R, 4S)5 (R) - 3, 4-dihydroxi-5 - (hydroximetyl) - tetrahydro-2-furan] - 6 - [(2, 2-ifniletil) amine] - N - [2 - (1-piserinil) ethyl] - 9h-purina-2-carboxamida or one of the acceptable salts or prescription solutions; (b) as the terminator of a brominated two kidney adenosine receptor of salmeterol. The combination is an effective method for the treatment of respiratory obstructive diseases.