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PROTEIN RIB, A CELL SURFACE PROTEIN CONFESSING IMMUNITY TO MANY STREPTOPES OF GROUP B ESTREPTOCOCKS: PROCESS FOR PURIFICATION OF PROTEIN, REAGENT CASE AND PHARMACEUTICAL COMPOSITION
PROTEIN RIB, A CELL SURFACE PROTEIN CONFESSING IMMUNITY TO MANY STREPTOPES OF GROUP B ESTREPTOCOCKS: PROCESS FOR PURIFICATION OF PROTEIN, REAGENT CASE AND PHARMACEUTICAL COMPOSITION
This invention relates to a new protein, designated Rib, and subfragments, multiples or variants thereof, which confers protective immunity against infection with many group B streptococcal strains, in particular those of serotype III. The invention includes a procedure for purification of the protein, a procedure for preparation of highly specific antibodies, a reagent kit, a DNA sequence encoding the protein and a pharmaceutical composition comprising the protein or fragments or variants thereof.
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