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Crystals structure of the mouse apoptosis-inducing factor aif and applications thereof
Crystals structure of the mouse apoptosis-inducing factor aif and applications thereof
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机译:小鼠凋亡诱导因子aif的晶体结构及其应用
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摘要
Structural features of Apoptosis-inducing Factor (AIF), a flavoprotein that can stimulate a caspase-independent cell-death pathway. Structure-based screening, identification and design of molecules that modulate AIF functional activities, including apoptosis and redox activity. Molecules useful for modulating apoptosis or AIF redox activity obtained by these methods.
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