USE OF HUMAN NEURAL STEM CELLS SECRETING GDNF FOR TREATMENT OF PARKINSON'S AND OTHER NEURODEGENERATIVE DISEASES

摘要

A method of treating brain disorders involving loss of cells that respond to GDNF is disclosed. In one embodiment, the invention comprises the steps of (a) transducing human neural stem cells with glial-derived neurotrophic factor (GDNF), wherein the GDNF gene is under control of an inducible promoter system, and (b) transplanting the transduced cells into the brain of a patient.