CELL TRANSFORMATION USING A SINGLE CHIP SILICON MICROFABRICATED ARRAY INCORPORATING INTEGRATED MICRO-PIERCING INJECTORS

摘要

The present invention provides an improved methodology for the introduction of specific molecules into cells, or the removal of material from cells, over the current state of the art. In particular, the invention provides an efficient means for these procedures to be undertaken on a high throughput level using minimally skilled expertise and handling by providing a microfabricated silicon array substrate having a simplified device fabrication strategy, whereby a single device component performs the transformation process rendering a more durable and robust device.