REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS

摘要

Preventives and/or remedies for diseases, which are induced, worsened or made to recrudesce by stressors, comprising mitochondrial benzodiazepine receptor (MBR) antagonists such as compounds represented by the following general formula (I) as the active ingredient: (I) wherein each symbol is as defined in the description. Because of inhibiting the reproduction of neurosteroids, the compounds having an MBR antagonistic activity are useful as preventives and/or remedies for diseases which are induced, worsened or made to recrudesce by stressors.