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Use of esters or amides of hydroxylated carboxylic acid as solubilizers

机译:羟基化羧酸的酯或酰胺作为增溶剂的用途

摘要

The use of hydroxylated carboxylic acid esters and amides as stabilizers is new. Certain of the hydroxylated carboxylic acid esters are also new. The hydroxylated carboxylic acid esters and amides are compounds of formula (I): R1 = H; 1-22C acyl; or a group of formula (a): R2 = H; 1-16C alkyl; or 2-12C alkenyl; R3 = 1-16C alkylene or 2-16C alkenylene; R4 = 1-12C alkyl; 2-12C alkenyl; or 1-12C acyl; A = -N(R5)-R6-; B = -CH2-CH2-O-; -CH2-CH2-CH2-O-; and/or -CH(CH3)-CH2-O-; R5 = H; 1-12C alkyl; 2-12C alkenyl; 1-12C acyl; or -(B)z-R4; R6 = -CH2-CH2-; -CH2-CH2-CH2-; or -CH(CH3)-CH2-; R7 = 1-16C alkylene; 2-16C alkenylene; or the residue of a dimerized fatty acid; x = 1-6; y = 0 or 1; z = 8-18. Independent claims are also included for pharmaceutical, cosmetic and food compositions containing a compound (I).
机译:羟基化羧酸酯和酰胺作为稳定剂的使用是新的。某些羟基化羧酸酯也是新的。羟基化的羧酸酯和酰胺是式(I)的化合物:R 1 = H; 1-22C酰基;或一组式(a):R 2 = H;或1-16C烷基;或2-12C烯基; R 3 = 1-16C亚烷基或2-16C亚烯基; R 4 = 1-12C烷基; 2-12C烯基;或1-12C酰基; A = -N(R 5)-R 6-; B = -CH2-CH2-O-; -CH2-CH2-CH2-O-;和/或-CH(CH3)-CH2-O-; R 5 = H; 1-12C烷基; 2-12C烯基; 1-12C酰基;或-(B)z-R 4;或R 6 = -CH 2 -CH 2-; -CH2-CH2-CH2-;或-CH(CH3)-CH2-; R 7 = 1-16C亚烷基; 2-16C亚烯基;或二聚脂肪酸的残基; x = 1-6; y = 0或1; z = 8-18。对于包含化合物(I)的药物,化妆品和食品组合物也包括独立权利要求。

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